Pentoxifylline may potentiate the effect of' anti-hypertensive agents and the dosage of the latter may need to be reduced.
Pentoxifylline should not be given concomitantly with Ketorolac as there is increased risk of bleeding and/or prolongation of prothrombin time.
Concomitant administration of Pentoxifylline and Theophylline may increase Theophylline levels in some patients. Therefore there may be an increase in and intensification of adverse effects of Theophylline.